To examine potential long-term impacts of COVID-19 on educational systems, the KIX Observatory on COVID-19 Responses in Educational Systems in Africa analyzed stakeholder perspectives from seven countries in Africa: Burkina Faso, Kenya, Malawi, Mali, Mozambique, Niger, and Nigeria. The stakeholders comprised 45 senior Ministry of Education officials related to programs and planning at headquarters and regional levels, as well as 28 non-state actors that work closely with ministries of education, in the seven countries. The aim of this policy brief is to call upon governments in Africa to take practical actions to mitigate the long-term impacts of the COVID-19 pandemic on educational systems. The brief presents high-level findings followed by practical policy and practice messages; it ends with a conclusion.