All education decision makers want essentially the same thing: to know what works in meeting education’s greatest challenges. Those challenges revolve around three main issues: (1) how to get all children into school; (2) how to keep all children in school while ensuring that each child benefits from a meaningful education; and (3) how to ensure that all children, young people and adults have the knowledge, skills and abilities to make a positive difference in their own lives and in the lives of others. A great many interventions and initiatives have been applied within education systems in developing countries. This ‘Super Synthesis’ of the evidence draws from 18 systematic reviews, meta-analyses and comparative reviews of ‘what works’ in education for development. By condensing this vast literature into an operational guideline, the Super Synthesis identifies which interventions have been shown to have the greatest impact on education quality and participation in a development sector context.